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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Mcm2p
Description
Protein involved in DNA replication; component of the Mcm2-7 hexameric helicase complex that binds chromatin as a part of the pre-replicative complex; relative distribution to the nucleus increases upon DNA replication stress
GO Terms:
Biological Process
level 3:
cell cycle
level 5:
mitotic DNA replication initiation
level 5:
pre-replicative complex assembly involved in nuclear cell cycle DNA replication
level 5:
cellular response to DNA damage stimulus
level 6:
DNA replication
level 6:
DNA replication initiation
level 7:
negative regulation of DNA helicase activity
level 7:
DNA strand elongation involved in DNA replication
level 8:
DNA unwinding involved in DNA replication
level 9:
double-strand break repair via break-induced replication
level 9:
DNA duplex unwinding
GO Terms:
Molecular Function
level 3:
helicase activity
level 3:
hydrolase activity
level 3:
chromatin binding
level 4:
nucleotide binding
level 5:
single-stranded DNA helicase activity
level 5:
DNA binding
level 5:
3'-5' DNA helicase activity
level 5:
metal ion binding
level 6:
ATP binding
level 6:
single-stranded DNA binding
level 7:
zinc ion binding
level 8:
DNA replication origin binding
GO Terms:
Cellular Component
level 3:
cytoplasm
level 3:
MCM complex
level 4:
nuclear pre-replicative complex
level 4:
DNA replication preinitiation complex
level 4:
replication fork protection complex
level 5:
CMG complex
level 5:
nucleus
External source
Open in SGD