S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ubc4p
Description	Ubiquitin-conjugating enzyme (E2); key E2 partner with Ubc1p for the anaphase-promoting complex (APC); mediates degradation of abnormal or excess proteins, including calmodulin and histone H3; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response; UBC4 has a paralog, UBC5, that arose from the whole genome duplication
GO Terms: Biological Process	level 7: cytoplasm protein quality control by the ubiquitin-proteasome system level 8: ubiquitin-dependent protein catabolic process level 8: mitochondria-associated ubiquitin-dependent protein catabolic process level 8: protein ubiquitination level 9: protein monoubiquitination level 9: protein polyubiquitination level 9: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO Terms: Molecular Function	level 3: transferase activity level 3: protein-macromolecule adaptor activity level 4: proteasome binding level 4: nucleotide binding level 5: ubiquitin binding level 5: ubiquitin-protein transferase activity level 6: ATP binding level 6: ubiquitin conjugating enzyme activity level 6: ubiquitin protein ligase binding
GO Terms: Cellular Component	level 3: cytoplasm level 4: ubiquitin ligase complex level 5: nucleus
External source	Open in SGD