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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Sif2p
Description
WD40 repeat-containing subunit of Set3C histone deacetylase complex; complex represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus
GO Terms:
Biological Process
level 5:
chromatin organization
level 7:
regulation of DNA-templated transcription
level 7:
histone deacetylation
level 7:
negative regulation of meiotic nuclear division
level 8:
regulation of transcription by RNA polymerase II
level 8:
positive regulation of stress-activated MAPK cascade
level 8:
negative regulation of DNA-templated transcription
GO Terms:
Molecular Function
level 1:
molecular_function
level 4:
transcription corepressor activity
GO Terms:
Cellular Component
level 4:
Set3 complex
level 4:
histone deacetylase complex
level 4:
Rpd3L-Expanded complex
level 5:
nucleus
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