S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Cks1p
Description	Cyclin-dependent protein kinase regulatory subunit and adaptor; interacts with Cdc28p (aka Cdk1p); required for G1/S and G2/M phase transitions and budding; mediates phosphorylation and degradation of Sic1p; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters; human homologs CKS1B and CKS2 can each complement yeast cks1 null mutant
GO Terms: Biological Process	level 3: cell cycle level 3: cell division level 4: regulation of catalytic activity level 6: regulation of mitotic cell cycle level 7: positive regulation of cyclin-dependent protein serine/threonine kinase activity level 8: regulation of transcription by RNA polymerase II level 9: activation of protein kinase activity level 9: positive regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 4: histone binding level 5: ubiquitin binding level 6: protein kinase activator activity level 6: cyclin-dependent protein serine/threonine kinase regulator activity level 6: protein kinase binding level 7: cyclin-dependent protein serine/threonine kinase activator activity
GO Terms: Cellular Component	level 3: cytoplasm level 5: nucleus level 6: SCF ubiquitin ligase complex level 8: cyclin-dependent protein kinase holoenzyme complex
External source	Open in SGD