S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Isw1p
Description	ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; with Ioc3p forms Isw1a complex involved in repression of transcription initiation; with Ioc2p and Ioc4p forms Isw1b complex involved in regulation of transcription elongation; Isw1b recruited to ORFs by H3K36 methylation and acts with Chd1p to prevent trans-histone exchange over coding regions; Isw1p import into nucleus depends on C-terminal bipartite nuclear targeting signal KRIR X19 KKAK
GO Terms: Biological Process	level 4: sister chromatid cohesion level 5: chromatin organization level 6: chromatin remodeling level 6: regulation of chromatin organization level 7: DNA-templated transcription elongation level 8: termination of RNA polymerase I transcription level 8: termination of RNA polymerase II transcription level 9: positive regulation of transcription by RNA polymerase II level 10: regulation of transcriptional start site selection at RNA polymerase II promoter
GO Terms: Molecular Function	level 3: ATP-dependent activity, acting on DNA level 3: hydrolase activity level 3: helicase activity level 3: ATP hydrolysis activity level 4: nucleosome binding level 4: nucleotide binding level 4: ATP-dependent chromatin remodeler activity level 5: DNA binding level 6: transcription cis-regulatory region binding level 6: ATP binding level 8: rDNA binding
GO Terms: Cellular Component	level 3: nucleolar chromatin level 5: nucleus level 7: Isw1a complex level 7: Isw1b complex
External source	Open in SGD