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Gene Ontology Information

Protein Name Dut1p
Description Deoxyuridine triphosphate diphosphatase (dUTPase); catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability; also has diphosphatase activity on deoxyinosine triphosphate; human homolog DUT allows growth of yeast haploid dut1 null mutant after sporulation of heterozygous diploid
GO Terms:
Biological Process		 level 6: nucleotide metabolic process external link
level 8: dUTP catabolic process external link
level 8: dITP catabolic process external link
level 9: dUMP biosynthetic process external link
level 9: pyrimidine deoxyribonucleoside triphosphate catabolic process external link
GO Terms:
Molecular Function		 level 3: hydrolase activity external link
level 5: metal ion binding external link
level 6: magnesium ion binding external link
level 8: dITP diphosphatase activity external link
level 8: dUTP diphosphatase activity external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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