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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Chk1p
Description
Serine/threonine kinase and DNA damage checkpoint effector; mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase
GO Terms:
Biological Process
level 3:
cell cycle
level 3:
signal transduction
level 5:
cellular response to DNA damage stimulus
level 6:
protein phosphorylation
level 6:
mitotic G2 DNA damage checkpoint signaling
level 6:
DNA damage checkpoint signaling
level 6:
phosphorylation
level 7:
replication fork protection
GO Terms:
Molecular Function
level 3:
transferase activity
level 4:
nucleotide binding
level 4:
protein kinase activity
level 5:
kinase activity
level 5:
protein serine/threonine kinase activity
level 6:
ATP binding
GO Terms:
Cellular Component
level 3:
cytoplasm
level 4:
site of double-strand break
level 5:
nucleus
External source
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