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Gene Ontology Information

Protein Name Dpb3p
Description Third-largest subunit of DNA polymerase II (DNA polymerase epsilon); required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; stabilizes the interaction of Pol epsilon with primer-template DNA, positively affecting the processivity of the polymerase and exonuclease activities of Pol epsilon; mRNA abundance peaks at the G1/S boundary of the cell cycle; DPB3 has a paralog, DLS1, that arose from the whole genome duplication
GO Terms:
Biological Process
level 4: regulation of catalytic activity external link
level 6: nucleic acid phosphodiester bond hydrolysis external link
level 6: DNA replication external link
level 7: DNA-templated DNA replication external link
level 8: leading strand elongation external link
level 9: error-prone translesion synthesis external link
GO Terms:
Molecular Function
level 5: DNA polymerase processivity factor activity external link
level 5: protein heterodimerization activity external link
level 6: double-stranded DNA binding external link
level 6: single-stranded DNA binding external link
level 9: single-stranded DNA 3'-5' exodeoxyribonuclease activity external link
GO Terms:
Cellular Component
level 4: epsilon DNA polymerase complex external link
level 5: nucleus external link
level 6: CHRAC external link
External source Open in SGD external link
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