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Gene Ontology Information

Protein Name Stp22p
Description Component of the ESCRT-I complex; ESCRT-I is involved in ubiquitin-dependent sorting of proteins into the endosome; prevents polyubiquitination of the arrestin-related protein Rim8p, thereby directing its monoubiquitination by Rsp5p; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype;
GO Terms:
Biological Process
level 5: protein modification process external link
level 5: protein transport external link
level 6: late endosome to vacuole transport external link
level 6: protein targeting to membrane external link
level 6: protein targeting to vacuole external link
level 6: endosome to lysosome transport external link
level 7: reticulophagy external link
level 8: ATP export external link
level 9: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway external link
level 11: negative regulation of protein polyubiquitination external link
GO Terms:
Molecular Function
level 5: ubiquitin binding external link
GO Terms:
Cellular Component
level 3: membrane external link
level 3: cytoplasm external link
level 3: cytosol external link
level 4: ESCRT I complex external link
level 4: endosome external link
level 5: cytoplasmic side of plasma membrane external link
level 6: late endosome membrane external link
External source Open in SGD external link
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