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Gene Ontology Information

Protein Name Snt1p
Description Set3C histone deacetylase scaffold; can act as prion [ESI+] (Expressed Subtelomeric Information) that drives emergence and transgenerational inheritance of activated chromatin state; prion conformer is triggered by transient Snt1p phosphorylation upon cell cycle arrest; [ESI+] reshapes the activity Set3C, recruiting RNAPII, interfering with Rap1p binding to activate genes in otherwise repressed subtelomeric domains; relocalizes to cytosol in response to hypoxia
GO Terms:
Biological Process
level 7: regulation of DNA-templated transcription external link
level 8: regulation of transcription by RNA polymerase II external link
level 8: positive regulation of stress-activated MAPK cascade external link
GO Terms:
Molecular Function
level 1: molecular_function external link
level 5: DNA binding external link
GO Terms:
Cellular Component
level 3: cytosol external link
level 4: Set3 complex external link
level 4: Rpd3L-Expanded complex external link
level 5: nucleus external link
External source Open in SGD external link
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