S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rad18p
Description	E3 ubiquitin ligase; forms heterodimer with Rad6p to monoubiquitinate PCNA-K164; heterodimer binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; required for postreplication repair; SUMO-targeted ubiquitin ligase (STUbl) that contains a SUMO-interacting motif (SIM) which stimulates its ubiquitin ligase activity towards the sumoylated form of PCNA
GO Terms: Biological Process	level 5: cellular response to DNA damage stimulus level 6: DNA repair level 7: postreplication repair level 8: protein ubiquitination level 8: error-free postreplication DNA repair level 9: protein monoubiquitination level 9: error-free translesion synthesis level 9: DNA duplex unwinding level 9: error-prone translesion synthesis
GO Terms: Molecular Function	level 3: transferase activity level 5: single-stranded DNA helicase activity level 5: DNA binding level 5: metal ion binding level 6: single-stranded DNA binding level 6: ubiquitin protein ligase activity level 7: zinc ion binding
GO Terms: Cellular Component	level 3: chromatin level 5: Rad6-Rad18 complex level 5: nucleus
External source	Open in SGD