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Gene Ontology Information

Protein Name Abp1p
Description Actin-binding protein of the cortical actin cytoskeleton; important for activation of actin nucleation mediated by the Arp2/Arp3 complex; inhibits actin filament elongation at the barbed-end; phosphorylation within its proline-rich region, mediated by Cdc28p and Pho85p, protects Abp1p from PEST sequence-mediated proteolysis; mammalian homolog of HIP-55 (hematopoietic progenitor kinase 1 [HPK1]-interacting protein of 55 kDa)
GO Terms:
Biological Process
level 6: actin cortical patch assembly external link
level 8: regulation of actin filament polymerization external link
level 8: protein localization to actin cortical patch external link
level 9: positive regulation of Arp2/3 complex-mediated actin nucleation external link
level 10: barbed-end actin filament capping external link
GO Terms:
Molecular Function
level 4: actin filament binding external link
level 5: actin binding external link
GO Terms:
Cellular Component
level 3: site of polarized growth external link
level 3: cytoplasm external link
level 4: actin cortical patch external link
level 4: mating projection tip external link
level 4: plasma membrane external link
level 4: cell cortex external link
level 5: cytoskeleton external link
level 6: cortical actin cytoskeleton external link
level 7: actin filament external link
External source Open in SGD external link
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