S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Cdc53p
Description	Cullin; structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation; human homolog CUL1 can complement yeast cdc53 null mutant
GO Terms: Biological Process	level 3: cell cycle level 3: cell division level 5: G1/S transition of mitotic cell cycle level 5: G2/M transition of mitotic cell cycle level 8: ubiquitin-dependent protein catabolic process level 8: protein ubiquitination level 8: SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO Terms: Molecular Function	level 3: protein-macromolecule adaptor activity level 5: ubiquitin-protein transferase activity level 6: ubiquitin protein ligase binding level 6: ubiquitin protein ligase activity level 8: DNA replication origin binding
GO Terms: Cellular Component	level 3: cytoplasm level 5: cullin-RING ubiquitin ligase complex level 5: nucleus level 6: SCF ubiquitin ligase complex
External source	Open in SGD