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Gene Ontology Information

Protein Name Scm3p
Description Nonhistone component of centromeric chromatin; binds to histone H3 variant, Cse4p, and recruits it to centromeres; involved in the assembly and maintenance of Cse4-H4 at centromeres; required for kinetochore assembly and G2/M progression; may protect Cse4p from ubiquitination; homolog of mammalian HJURP
GO Terms:
Biological Process		 level 3: chromosome segregation external link
level 5: G2/M transition of mitotic cell cycle external link
level 7: kinetochore assembly external link
level 8: protein localization to chromosome, centromeric region external link
level 8: negative regulation of ubiquitin-dependent protein catabolic process external link
GO Terms:
Molecular Function		 level 4: histone binding external link
level 5: CENP-A containing nucleosome binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: condensed chromosome, centromeric region external link
level 5: nucleus external link
External source Open in SGD external link
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