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manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Msh5p
Description
Protein of the MutS family; forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans
GO Terms:
Biological Process
level 4:
reciprocal meiotic recombination
level 4:
chiasma assembly
level 5:
cellular response to DNA damage stimulus
level 6:
DNA repair
level 7:
mismatch repair
GO Terms:
Molecular Function
level 4:
ATP-dependent DNA damage sensor activity
level 4:
nucleotide binding
level 5:
DNA binding
level 6:
double-stranded DNA binding
level 6:
ATP binding
level 7:
mismatched DNA binding
level 7:
four-way junction DNA binding
level 7:
Y-form DNA binding
level 7:
D-loop DNA binding
GO Terms:
Cellular Component
level 4:
MutSgamma complex
level 5:
nucleus
level 6:
nuclear chromosome
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