S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Cdc9p
Description	DNA ligase I found in nucleus and mitochondria; essential enzyme that joins Okazaki fragments during DNA replication; also acts in ribonucleotide excision repair, base excision repair, and recombination; DNA ligase I mutants trigger ubiquitination of PCNA at K107, facilitating Rad59p-mediated bypass of unligated Okazaki fragments; human homolog LIG1 can complement yeast cdc9 temperature-sensitive mutant at restrictive temperature
GO Terms: Biological Process	level 3: cell cycle level 3: cell division level 4: mitotic cell cycle level 5: Okazaki fragment processing involved in mitotic DNA replication level 5: cellular response to DNA damage stimulus level 6: DNA replication level 6: DNA ligation level 6: DNA biosynthetic process level 6: DNA repair level 6: DNA recombination level 7: maintenance of DNA trinucleotide repeats level 7: base-excision repair level 7: nucleotide-excision repair level 8: lagging strand elongation
GO Terms: Molecular Function	level 3: ligase activity level 4: nucleotide binding level 5: metal ion binding level 5: DNA binding level 5: DNA ligase activity level 6: DNA ligase (ATP) activity level 6: ATP binding
GO Terms: Cellular Component	level 3: cytoplasm level 4: mitochondrion level 5: nucleus
External source	Open in SGD