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Gene Ontology Information

Protein Name Maf1p
Description Highly conserved negative regulator of RNA polymerase III; involved in tRNA processing and stability; inhibits tRNA degradation via rapid tRNA decay (RTD) pathway; binds N-terminal domain of Rpc160p subunit of Pol III to prevent closed-complex formation; regulated by phosphorylation mediated by TORC1, protein kinase A, Sch9p, casein kinase 2; localizes to cytoplasm during vegetative growth and translocates to nucleus and nucleolus under stress conditions
GO Terms:
Biological Process		 level 9: negative regulation of transcription by RNA polymerase III external link
level 10: transfer RNA gene-mediated silencing external link
GO Terms:
Molecular Function		 level 7: RNA polymerase III core binding external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: nucleus external link
level 5: nucleolus external link
External source Open in SGD external link
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