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Gene Ontology Information

Protein Name Nsi1p
Description RNA polymerase I termination factor; binds to rDNA terminator element, required for efficient Pol I termination; required for rDNA silencing at NTS1; facilities association of Sir2p with NTS1, contributes to rDNA stability and cell longevity; interacts physically with Fob1p and RENT subunits, Sir2p and Net1p; may interact with ribosomes, based on co-purification experiments; Myb-like DNA-binding protein; NSI1 has a paralog, REB1, that arose from the whole genome duplication
GO Terms:
Biological Process		 level 6: rDNA heterochromatin formation external link
level 7: regulation of DNA-templated transcription external link
level 8: termination of RNA polymerase I transcription external link
GO Terms:
Molecular Function		 level 3: DNA-binding transcription factor activity external link
level 5: DNA binding external link
level 6: transcription cis-regulatory region binding external link
GO Terms:
Cellular Component		 level 5: rDNA heterochromatin external link
level 5: nucleus external link
level 5: nucleolus external link
External source Open in SGD external link
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