S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Vms1p
Description	Peptidyl-tRNA hydrolase that releases stalled peptides from ribosomes, component of a Cdc48p-complex; involved in protein quality control; exhibits cytosolic and ER-membrane localization; contributes to ER-associated degradation (ERAD) of specific substrates at a step after their ubiquitination; translocates to mitochondria under oxidative stress and forms a complex with Cdc48p and Npl4p that is required for ubiquitin-mediated mitochondria-associated protein degradation (MAD)
GO Terms: Biological Process	level 7: nuclear protein quality control by the ubiquitin-proteasome system level 7: ubiquitin-dependent ERAD pathway level 8: mitochondria-associated ubiquitin-dependent protein catabolic process
GO Terms: Molecular Function	level 5: metal ion binding level 6: aminoacyl-tRNA hydrolase activity level 7: zinc ion binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: cytosol level 3: membrane level 4: mitochondrion level 4: endoplasmic reticulum level 5: endoplasmic reticulum membrane level 5: ribosome level 5: Cdc48p-Npl4p-Vms1p AAA ATPase complex
External source	Open in SGD