S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dbf4p
Description	Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress; co-expression of human CDC7 and DBF4 complements single cdc7 or dbf4 null mutations or the cdc7 dbf4 double null mutation
GO Terms: Biological Process	level 3: cell division level 3: meiotic cell cycle level 3: cell cycle level 3: chromosome segregation level 4: premeiotic DNA replication level 5: mitotic DNA replication checkpoint signaling level 6: DNA replication level 6: DNA replication initiation level 7: regulation of cell cycle phase transition level 8: positive regulation of protein kinase activity level 8: positive regulation of meiosis I level 8: positive regulation of nuclear cell cycle DNA replication level 9: positive regulation of protein serine/threonine kinase activity level 9: negative regulation of exit from mitosis level 9: positive regulation of DNA replication initiation
GO Terms: Molecular Function	level 4: nucleic acid binding level 5: metal ion binding level 5: DNA binding level 7: protein serine/threonine kinase activator activity level 7: zinc ion binding level 8: DNA replication origin binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: chromatin level 4: chromosome, centromeric region level 4: Dbf4-dependent protein kinase complex level 5: nucleus
External source	Open in SGD