S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Doa4p
Description	Ubiquitin hydrolase; deubiquitinates intralumenal vesicle (ILVs) cargo proteins; required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins destined for the vacuole; DOA4 has a paralog, UBP5, that arose from the whole genome duplication
GO Terms: Biological Process	level 4: ubiquitin recycling level 5: free ubiquitin chain depolymerization level 5: proteolysis level 6: endocytosis level 7: intralumenal vesicle formation level 7: protein deubiquitination level 7: regulation of DNA replication level 8: ATP export level 8: ubiquitin-dependent protein catabolic process level 9: ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
GO Terms: Molecular Function	level 3: hydrolase activity level 4: peptidase activity level 5: cysteine-type peptidase activity level 6: cysteine-type deubiquitinase activity level 7: zinc ion binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: membrane level 3: cytosol level 4: proteasome complex level 4: mitochondrion level 4: endosome level 6: late endosome membrane
External source	Open in SGD