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Gene Ontology Information

Protein Name Trm82p
Description Noncatalytic subunit of a tRNA methyltransferase complex; Trm8p and Trm82p comprise an enzyme that catalyzes a methyl-transfer from S-adenosyl-l-methionine to the N(7) atom of guanine at position 46 in tRNA; Trm8 lacks catalytic activity if not bound to Trm82p; relocalizes to the cytosol in response to hypoxia; mutation in human ortholog WDR4 causes microcephalic primordial dwarfism
GO Terms:
Biological Process		 level 4: regulation of catalytic activity external link
level 6: tRNA methylation external link
level 6: RNA (guanine-N7)-methylation external link
level 7: tRNA (guanine-N7)-methylation external link
level 8: tRNA processing external link
GO Terms:
Molecular Function		 level 4: enzyme activator activity external link
level 8: tRNA (guanine-N7-)-methyltransferase activity external link
GO Terms:
Cellular Component		 level 3: cytosol external link
level 5: tRNA methyltransferase complex external link
level 5: nucleus external link
level 6: tRNA (m7G46) methyltransferase complex external link
External source Open in SGD external link
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