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Gene Ontology Information

Protein Name Sup35p
Description Translation termination factor eRF3; has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that modifies cellular fitness, alters translational fidelity by affecting reading frame selection, and results in a nonsense suppressor phenotype; many stress-response genes are repressed in the presence of [PSI(+)]
GO Terms:
Biological Process		 level 5: translation external link
level 6: translational termination external link
level 7: nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay external link
GO Terms:
Molecular Function		 level 4: nucleotide binding external link
level 5: ribosome binding external link
level 6: mRNA binding external link
level 6: translation release factor activity external link
level 6: GTP binding external link
level 8: GTPase activity external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 3: cytosol external link
level 3: translation release factor complex external link
level 5: cytoplasmic stress granule external link
External source Open in SGD external link
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