S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Upc2p
Description	Sterol regulatory element binding protein; induces sterol biosynthetic genes, upon sterol depletion; acts as a sterol sensor, binding ergosterol in sterol rich conditions; relocates from intracellular membranes to perinuclear foci upon sterol depletion; redundant activator of filamentation with ECM22, up-regulating the expression of filamentous growth genes; contains a Zn[2]-Cys[6] binuclear cluster; UPC2 has a paralog, ECM22, that arose from the whole genome duplication
GO Terms: Biological Process	level 5: cellular response to hypoxia level 7: regulation of DNA-templated transcription level 8: regulation of transcription by RNA polymerase II level 9: positive regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 4: DNA-binding transcription factor activity, RNA polymerase II-specific level 5: metal ion binding level 5: DNA-binding transcription activator activity, RNA polymerase II-specific level 5: DNA binding level 7: zinc ion binding level 8: RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO Terms: Cellular Component	level 3: membrane level 3: perinuclear region of cytoplasm level 3: cytoplasm level 5: nucleus
External source	Open in SGD