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Gene Ontology Information

Protein Name Adk1p
Description Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence; protein abundance increases in response to DNA replication stress; mutations affecting Adk1p catalytic activity deregulate expression of phosphate utilization genes PHO5 and PHO84; human homolog AK1 can complement yeast adk1 mutant
GO Terms:
Biological Process
level 4: nucleobase-containing compound metabolic process external link
level 6: DNA replication initiation external link
level 6: nucleotide metabolic process external link
level 6: phosphorylation external link
level 7: nucleoside monophosphate phosphorylation external link
level 8: pre-replicative complex assembly external link
level 8: AMP metabolic process external link
level 8: ATP metabolic process external link
level 9: ADP biosynthetic process external link
GO Terms:
Molecular Function
level 3: transferase activity external link
level 4: nucleotide binding external link
level 5: kinase activity external link
level 5: phosphotransferase activity, phosphate group as acceptor external link
level 6: nucleobase-containing compound kinase activity external link
level 6: ATP binding external link
level 7: adenylate kinase activity external link
level 8: DNA replication origin binding external link
GO Terms:
Cellular Component
level 3: cytosol external link
level 3: cytoplasm external link
level 4: mitochondrion external link
level 6: mitochondrial intermembrane space external link
External source Open in SGD external link
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