S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Ccc2p
Description	Cu(+2)-transporting P-type ATPase; required for export of copper from the cytosol into an extracytosolic compartment; similar to human proteins involved in Menkes and Wilsons diseases; protein abundance increases in response to DNA replication stress; affects TBSV model (+)RNA virus replication by regulating copper metabolism; human homologs ATP7A and ATP7B both complement yeast null mutant
GO Terms: Biological Process	level 3: transmembrane transport level 5: ion transport level 6: cation transport level 8: copper ion export level 9: cellular iron ion homeostasis level 9: copper ion transport level 10: copper ion homeostasis
GO Terms: Molecular Function	level 3: ATP hydrolysis activity level 4: nucleotide binding level 4: ATPase-coupled cation transmembrane transporter activity level 5: P-type monovalent copper transporter activity level 5: P-type divalent copper transporter activity level 5: metal ion binding level 6: ATP binding level 7: copper ion binding
GO Terms: Cellular Component	level 3: membrane level 4: integral component of membrane level 4: Golgi apparatus level 6: trans-Golgi network transport vesicle membrane
External source	Open in SGD