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Gene Ontology Information

Protein Name Hpt1p
Description Dimeric hypoxanthine-guanine phosphoribosyltransferase; catalyzes the transfer of the phosphoribosyl portion of 5-phosphoribosyl-alpha-1-pyrophosphate to a purine base (either guanine or hypoxanthine) to form pyrophosphate and a purine nucleotide (either guanosine monophosphate or inosine monophosphate); mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome
GO Terms:
Biological Process
level 6: purine ribonucleoside salvage external link
level 7: hypoxanthine metabolic process external link
level 8: GMP salvage external link
level 8: IMP salvage external link
level 8: XMP salvage external link
GO Terms:
Molecular Function
level 3: transferase activity external link
level 4: glycosyltransferase activity external link
level 4: nucleotide binding external link
level 5: metal ion binding external link
level 6: phosphomannomutase activity external link
level 7: hypoxanthine phosphoribosyltransferase activity external link
level 7: guanine phosphoribosyltransferase activity external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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