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Gene Ontology Information

Protein Name Hsp31p
Description Methylglyoxalase that converts methylglyoxal to D-lactate; involved in oxidative stress resistance, diauxic shift, and stationary phase survival; has similarity to E. coli Hsp31 and C. albicans Glx3p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease and cancer; exists as a dimer and contains a putative metal-binding site; protein abundance increases in response to DNA replication stress
GO Terms:
Biological Process
level 4: chaperone-mediated protein folding external link
level 5: cellular response to nutrient levels external link
level 5: cellular response to oxidative stress external link
level 6: lactate biosynthetic process external link
level 7: methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione external link
GO Terms:
Molecular Function
level 2: protein folding chaperone external link
level 3: lyase activity external link
level 6: glyoxalase III activity external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 5: cytoplasmic stress granule external link
level 5: P-body external link
External source Open in SGD external link
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