S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Hyp2p
Description	Translation elongation factor eIF-5A; required for translation of proteins containing polyproline stretches, including Bni1p, and this leads to a requirement for mating projection formation; structural homolog of bacterial EF-P; undergoes an essential hypusination modification; HYP2 has a paralog, ANB1, that arose from the whole genome duplication; human EIF5A complements the inviability of the yeast hyp2 anb1 double null mutant
GO Terms: Biological Process	level 4: translational initiation level 5: translation level 6: translational elongation level 7: translational frameshifting level 8: positive regulation of translational termination level 9: positive regulation of translational elongation level 9: positive regulation of translational initiation level 11: positive regulation of cytoplasmic translational elongation through polyproline stretches
GO Terms: Molecular Function	level 5: ribosome binding level 5: RNA binding level 5: translation initiation factor activity level 5: translation elongation factor activity
GO Terms: Cellular Component	level 3: perinuclear region of cytoplasm level 3: cytoplasm level 4: mitochondrion
External source	Open in SGD