S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Npr2p
Description	Subunit of the Iml1p/SEACIT complex; SEACIT (Iml1p-Npr2p-Npr3p) is a subcomplex of the SEA complex, a coatomer-related complex that associates dynamically with the vacuole; Npr2p may have a structural or regulatory role, supporting Iml1p function as a GAP for the Rag family GTPase Gtr1p, and resulting in inhibition of TORC1 signaling in response to amino acid deprivation; SEACIT is required for non-nitrogen-starvation-induced autophagy; homolog of human tumor suppressor NPRL2
GO Terms: Biological Process	level 4: regulation of catalytic activity level 4: response to xenobiotic stimulus level 5: protein transport level 6: cellular response to nitrogen starvation level 7: positive regulation of cellular response to amino acid starvation level 7: regulation of autophagosome assembly level 7: urea transport level 8: positive regulation of autophagy level 8: proline transport level 9: negative regulation of TORC1 signaling
GO Terms: Molecular Function	level 1: molecular_function level 5: GTPase activator activity
GO Terms: Cellular Component	level 3: membrane level 3: Seh1-associated complex level 3: GATOR1 complex level 4: vacuole level 5: vacuolar membrane level 6: extrinsic component of fungal-type vacuolar membrane
External source	Open in SGD