S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Dld3p
Description	2-hydroxyglutarate transhydrogenase, and minor D-lactate dehydrogenase; converts D-2-hydroxyglutarate (D-2HG), an oncometabolite, to alpha-ketoglutarate in the presence of FAD, with concomitant reduction of pyruvate to D-lactate; minor lactate dehydrogenase activity; component of the retrograde regulon that consists of genes whose expression are stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source; located in the cytoplasm
GO Terms: Biological Process	level 3: filamentous growth level 6: lactate biosynthetic process
GO Terms: Molecular Function	level 2: catalytic activity level 3: oxidoreductase activity level 5: flavin adenine dinucleotide binding level 5: (D)-2-hydroxyglutarate-pyruvate transhydrogenase activity level 6: FAD binding level 6: D-lactate dehydrogenase (cytochrome) activity
GO Terms: Cellular Component	level 3: cytoplasm level 4: mitochondrion
External source	Open in SGD