S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Afg3p
Description	Mitochondrial inner membrane m-AAA protease component; mediates degradation of misfolded or unassembled proteins; also required for correct assembly of mitochondrial enzyme complexes; involved in cytoplasmic mRNA translation and aging; expression of human homolog AFG3L2 can complement yeast yta12 afg3 double mutant
GO Terms: Biological Process	level 5: protein import into mitochondrial matrix level 5: proteolysis level 6: signal peptide processing level 6: protein-containing complex assembly level 7: mitochondrial protein processing
GO Terms: Molecular Function	level 3: ATP-dependent peptidase activity level 3: hydrolase activity level 3: ATP hydrolysis activity level 4: peptidase activity level 4: nucleotide binding level 5: metal ion binding level 5: metallopeptidase activity level 6: metalloendopeptidase activity level 6: ATP binding level 7: zinc ion binding
GO Terms: Cellular Component	level 3: membrane level 3: mitochondrial inner boundary membrane level 4: integral component of membrane level 4: mitochondrion level 5: m-AAA complex level 6: mitochondrial inner membrane level 7: fungal-type vacuole membrane
External source	Open in SGD