Yeastract
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Gene Ontology Information

Protein Name Yen1p
Description Holliday junction resolvase; promotes template switching during break-induced replication (BIR), causing non-reciprocal translocations (NRTs); localization is cell-cycle dependent and regulated by Cdc28p phosphorylation; homolog of human GEN1; similar to S. cerevisiae endonuclease Rth1p
GO Terms:
Biological Process		 level 5: cellular response to DNA damage stimulus external link
level 6: nucleic acid phosphodiester bond hydrolysis external link
level 6: DNA repair external link
GO Terms:
Molecular Function		 level 3: hydrolase activity external link
level 5: nuclease activity external link
level 6: endonuclease activity external link
level 7: 5'-3' exonuclease activity external link
level 8: crossover junction endodeoxyribonuclease activity external link
level 8: 5'-flap endonuclease activity external link
level 9: double-stranded DNA 5'-3' exodeoxyribonuclease activity external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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