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Gene Ontology Information

Protein Name Mot2p
Description Ubiquitin-protein ligase subunit of the CCR4-NOT complex; with Ubc4p, ubiquitinates nascent polypeptide-associated complex subunits and histone demethyase Jhd2p; CCR4-NOT has roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; regulates levels of DNA Polymerase-{alpha} to promote efficient and accurate DNA replication
GO Terms:
Biological Process
level 6: proteasomal protein catabolic process external link
level 7: deadenylation-independent decapping of nuclear-transcribed mRNA external link
level 8: protein ubiquitination external link
level 9: protein polyubiquitination external link
level 10: positive regulation of transcription elongation by RNA polymerase II external link
GO Terms:
Molecular Function
level 4: nucleic acid binding external link
level 5: RNA binding external link
level 5: metal ion binding external link
level 5: ubiquitin-protein transferase activity external link
level 6: ubiquitin protein ligase activity external link
level 7: zinc ion binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 4: CCR4-NOT complex external link
level 4: CCR4-NOT core complex external link
level 5: nucleus external link
External source Open in SGD external link
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