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Gene Ontology Information

Protein Name Rnr1p
Description Major isoform of large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits; relative distribution to the nucleus increases upon DNA replication stress; RNR1 has a paralog, RNR3, that arose from the whole genome duplication
GO Terms:
Biological Process
level 2: metabolic process external link
level 6: DNA replication external link
level 6: deoxyribonucleotide biosynthetic process external link
GO Terms:
Molecular Function
level 2: catalytic activity external link
level 3: oxidoreductase activity external link
level 4: nucleotide binding external link
level 6: ATP binding external link
level 7: ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 4: ribonucleoside-diphosphate reductase complex external link
level 5: nucleus external link
External source Open in SGD external link
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