S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rad51p
Description	Strand exchange protein; forms helical filament with DNA that searches for homology; involved in recombinational repair of DNS DSBs during vegetative growth and meiosis; phosphorylation by Cdc28p in G2/M phase promotes DNA binding, strand invasion, and primer extension; L1 and L2 motifs of DNA binding site I have critical roles in ensuring DNA fidelity during meiotic recombination; RAD51 and RAD4 pathways confer resistance to benzo[a]pyrene dihydrodiol; homolog of Dmc1p and bacterial RecA
GO Terms: Biological Process	level 4: reciprocal meiotic recombination level 4: meiotic joint molecule formation level 4: chromosome organization involved in meiotic cell cycle level 5: cellular response to DNA damage stimulus level 5: DNA metabolic process level 6: heteroduplex formation level 6: strand invasion level 6: DNA repair level 6: mitotic recombination-dependent replication fork processing level 6: DNA recombination level 7: mitotic recombination level 7: telomere maintenance via recombination level 7: mitochondrial DNA repair level 7: nucleotide-excision repair level 7: double-strand break repair level 8: double-strand break repair via homologous recombination level 8: DNA recombinase assembly
GO Terms: Molecular Function	level 3: protein binding level 3: ATP-dependent activity, acting on DNA level 4: nucleotide binding level 4: ATP-dependent DNA damage sensor activity level 5: DNA strand exchange activity level 5: DNA binding level 6: ATP binding level 6: double-stranded DNA binding level 6: single-stranded DNA binding
GO Terms: Cellular Component	level 5: nucleus level 5: chromosome level 5: mitochondrial matrix level 6: nuclear chromosome level 6: condensed nuclear chromosome
External source	Open in SGD