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Modelling prediction
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[metab] Optimisation
manipulating gene expression
manipulating TF expression
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Gene Ontology Information
Locus Info
Protein Info
GO Info
Orthologs
Protein Name
Spt15p
Description
TATA-binding protein (TBP); general transcription factor that interacts with other factors to form the preinitiation complex at promoters; essential for viability, highly conserved; yeast gene can complement mutations in human homolog TBP
GO Terms:
Biological Process
level 4:
transposon integration
level 7:
DNA-templated transcription initiation
level 9:
nucleolar large rRNA transcription by RNA polymerase I
level 9:
RNA polymerase II preinitiation complex assembly
level 9:
RNA polymerase I preinitiation complex assembly
level 9:
RNA polymerase III preinitiation complex assembly
GO Terms:
Molecular Function
level 2:
general transcription initiation factor activity
level 3:
RNA polymerase II general transcription initiation factor activity
level 3:
RNA polymerase III general transcription initiation factor activity
level 3:
chromatin binding
level 5:
DNA binding
level 6:
DNA binding, bending
level 6:
RNA polymerase I general transcription initiation factor binding
level 6:
RNA polymerase II-specific DNA-binding transcription factor binding
level 7:
RNA polymerase III transcription regulatory region sequence-specific DNA binding
level 8:
RNA polymerase II core promoter sequence-specific DNA binding
GO Terms:
Cellular Component
level 5:
nucleus
level 5:
transcription factor TFIID complex
level 5:
transcription factor TFIIIB complex
External source
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