S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Bur6p
Description	Subunit of a heterodimeric NC2 transcription regulator complex; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha; complex also includes Ncb2p; bur6 ncb2 double mutation is functionally complemented by coexpression of human DRAP1 and DR1, although the single bur6 mutation is not complemented by its ortholog DRAP1
GO Terms: Biological Process	level 7: DNA-templated transcription elongation level 7: regulation of DNA-templated transcription level 8: transcription by RNA polymerase II level 9: positive regulation of transcription by RNA polymerase II level 9: RNA polymerase II preinitiation complex assembly level 9: negative regulation of transcription by RNA polymerase II
GO Terms: Molecular Function	level 3: chromatin binding level 3: transcription coregulator activity level 3: RNA polymerase II general transcription initiation factor activity level 4: transcription coactivator activity level 4: transcription corepressor activity level 5: protein heterodimerization activity level 6: TBP-class protein binding level 7: core promoter sequence-specific DNA binding
GO Terms: Cellular Component	level 5: negative cofactor 2 complex level 5: nucleus
External source	Open in SGD