S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rad3p
Description	5' to 3' DNA helicase; involved in nucleotide excision repair and transcription; subunit of RNA polII initiation factor TFIIH and of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein; mutant has aneuploidy tolerance; protein abundance increases in response to DNA replication stress
GO Terms: Biological Process	level 4: nucleobase-containing compound metabolic process level 5: cellular response to DNA damage stimulus level 6: regulation of transposition, RNA-mediated level 6: DNA repair level 7: nucleotide-excision repair level 7: phosphorylation of RNA polymerase II C-terminal domain level 7: nucleotide-excision repair, DNA incision level 8: nucleotide-excision repair, DNA duplex unwinding level 8: transcription by RNA polymerase II level 8: regulation of mitotic recombination level 9: positive regulation of mitotic recombination
GO Terms: Molecular Function	level 3: ATP-dependent activity, acting on DNA level 3: helicase activity level 3: hydrolase activity level 4: iron-sulfur cluster binding level 4: nucleic acid binding level 4: DNA helicase activity level 4: nucleotide binding level 5: metal ion binding level 5: 4 iron, 4 sulfur cluster binding level 5: DNA binding level 5: hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides level 5: 5'-3' DNA helicase activity level 6: damaged DNA binding level 6: ATP binding
GO Terms: Cellular Component	level 5: nucleus level 5: nucleotide-excision repair factor 3 complex level 5: transcription factor TFIIH holo complex level 5: transcription factor TFIIH core complex
External source	Open in SGD