S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Loc1p
Description	Nucleolar protein involved in the asymmetric localization of ASH1 mRNA; binds cooperatively with She2p to the E3 zip-code element in the 3'-UTR of the mRNA; constituent of 66S pre-ribosomal particles involved in pre-rRNA processing and nuclear export of the 60S subunit; may facilitate Rpl43p loading; required post-transcriptionally for efficient retrotransposition; absence results in decreased Ty1 Gag:GFP protein levels; relocalizes from nucleus to cytoplasm upon DNA replication stress
GO Terms: Biological Process	level 5: protein stabilization level 5: intracellular mRNA localization level 5: ribosomal large subunit export from nucleus level 6: mRNA transport level 6: ribosome biogenesis level 6: ribosomal large subunit biogenesis level 8: negative regulation of translation level 9: endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 9: endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) level 9: endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO Terms: Molecular Function	level 6: mRNA binding
GO Terms: Cellular Component	level 3: cytoplasm level 4: chaperone complex level 5: nucleus level 5: nucleolus level 5: preribosome, large subunit precursor
External source	Open in SGD