S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Cdh1p
Description	Activator of anaphase-promoting complex/cyclosome (APC/C); antagonist of the spindle assembly checkpoint; directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including: Cdc20p, Ase1p, Cin8p, Fin1p and Clb5p; partially active in metaphase, and fully active in anaphase; cell-cycle regulated
GO Terms: Biological Process	level 3: cell division level 3: cell cycle level 7: positive regulation of protein catabolic process level 8: negative regulation of mitotic spindle pole body separation level 8: positive regulation of ubiquitin-dependent protein catabolic process level 8: anaphase-promoting complex-dependent catabolic process level 8: positive regulation of ubiquitin protein ligase activity level 9: positive regulation of mitotic metaphase/anaphase transition level 9: positive regulation of mitotic actomyosin contractile ring disassembly level 9: deactivation of mitotic spindle assembly checkpoint level 10: positive regulation of anaphase-promoting complex-dependent catabolic process
GO Terms: Molecular Function	level 4: anaphase-promoting complex binding level 4: cyclin binding level 5: ubiquitin-protein transferase activator activity level 6: ubiquitin ligase activator activity
GO Terms: Cellular Component	level 3: cytoplasm level 5: nucleus level 5: anaphase-promoting complex
External source	Open in SGD