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Gene Ontology Information

Protein Name Alk1p
Description Atypical protein kinase; along with paralog, ALK2, required for proper spindle positioning and nuclear segregation following mitotic arrest, proper organization of cell polarity factors in mitosis, proper localization of formins and polarity factors, and survival in cells that activate spindle assembly checkpoint; regulates the morphogenesis checkpoint in response to polarity insults through inactivation of Mih1p; phosphorylated in response to DNA damage; similar to mammalian haspins
GO Terms:
Biological Process
level 3: cell cycle external link
level 4: mitotic cell cycle external link
level 4: intracellular signal transduction external link
level 5: cellular response to DNA damage stimulus external link
level 6: phosphorylation external link
level 6: mitotic morphogenesis checkpoint signaling external link
GO Terms:
Molecular Function
level 3: transferase activity external link
level 4: nucleotide binding external link
level 4: protein kinase activity external link
level 5: kinase activity external link
level 5: protein serine/threonine kinase activity external link
level 6: ATP binding external link
level 7: histone kinase activity (H3-T3 specific) external link
GO Terms:
Cellular Component
level 1: cellular_component external link
level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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