S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Rad6p
Description	Ubiquitin-conjugating enzyme (E2); involved in postreplication repair as a heterodimer with Rad18p, regulation of K63 polyubiquitination in response to oxidative stress, DSBR and checkpoint control as a heterodimer with Bre1p, ubiquitin-mediated N-end rule protein degradation as a heterodimer with Ubr1p, ERAD with Ubr1p in the absence of canonical ER membrane ligases, and Rpn4p turnover as part of proteasome homeostasis, in complex with Ubr2p and Mub1p
GO Terms: Biological Process	level 4: sporulation resulting in formation of a cellular spore level 5: cellular response to DNA damage stimulus level 5: meiotic DNA double-strand break formation level 5: stress-induced homeostatically regulated protein degradation pathway level 5: chromatin organization level 6: mitotic G1 DNA damage checkpoint signaling level 6: DNA repair level 7: cytoplasm protein quality control by the ubiquitin-proteasome system level 7: histone ubiquitination level 7: proteasome-mediated ubiquitin-dependent protein catabolic process level 7: ubiquitin-dependent ERAD pathway level 7: telomere maintenance via recombination level 7: DNA-templated transcription termination level 8: subtelomeric heterochromatin formation level 8: ubiquitin-dependent protein catabolic process level 8: ubiquitin-dependent protein catabolic process via the N-end rule pathway level 8: regulation of dipeptide transport level 8: histone monoubiquitination level 8: protein ubiquitination level 8: error-free postreplication DNA repair level 8: double-strand break repair via homologous recombination level 8: transcription by RNA polymerase II level 9: error-free translesion synthesis level 9: protein monoubiquitination level 9: DNA duplex unwinding level 9: error-prone translesion synthesis level 9: protein polyubiquitination level 10: protein K63-linked ubiquitination
GO Terms: Molecular Function	level 3: transferase activity level 4: nucleotide binding level 4: proteasome binding level 5: ubiquitin-protein transferase activity level 5: single-stranded DNA helicase activity level 6: single-stranded DNA binding level 6: ATP binding level 6: ubiquitin conjugating enzyme activity
GO Terms: Cellular Component	level 3: chromatin level 3: cytoplasm level 4: chromosome, telomeric region level 4: HULC complex level 4: UBR1-RAD6 ubiquitin ligase complex level 4: MUB1-RAD6-UBR2 ubiquitin ligase complex level 5: Rad6-Rad18 complex level 5: nucleus
External source	Open in SGD