S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Sgf73p
Description	Subunit of DUBm module of SAGA and SLIK; has roles in anchoring deubiquitination module (DUBm) into SAGA and SLIK complexes, maintaining organization and ubiquitin-binding conformation of Ubp8p, thereby contributing to overall DUBm activity; involved in preinitiation complex assembly at promoters; relocalizes to cytosol under hypoxia; human homolog ATXN7 implicated in spinocerebellar ataxia, and can complement yeast null mutant
GO Terms: Biological Process	level 4: regulation of catalytic activity level 5: chromatin organization level 6: mRNA export from nucleus level 6: protein-containing complex assembly level 7: RITS complex assembly level 7: regulation of protein localization to chromatin level 7: histone acetylation level 7: histone deubiquitination level 7: regulation of nucleocytoplasmic transport level 8: regulation of transcription by RNA polymerase II level 8: positive regulation of RNA polymerase II transcription preinitiation complex assembly
GO Terms: Molecular Function	level 2: structural molecule activity level 4: enzyme activator activity level 5: histone acetyltransferase activity level 7: zinc ion binding
GO Terms: Cellular Component	level 3: cytosol level 4: DUBm complex level 5: SAGA complex level 5: nucleus level 6: SLIK (SAGA-like) complex
External source	Open in SGD