Yeastract
Please fill in here our
user satisfaction survey
Thank you!
YEASTRACT+ INESC-ID IST IBB
Home > Go Back > View Contact/Credits     Tutorial     Help

 

Gene Ontology Information

Protein Name Mad1p
Description Coiled-coil protein involved in spindle-assembly checkpoint; required for inhibition of karyopherin/importin Pse1p (aka Kap121p) upon spindle assembly checkpoint arrest; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of anaphase promoting complex activity; forms a complex with Mad2p; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability
GO Terms:
Biological Process
level 3: cell cycle external link
level 3: cell division external link
level 5: mitotic spindle assembly checkpoint signaling external link
level 5: mitotic DNA integrity checkpoint signaling external link
level 5: attachment of mitotic spindle microtubules to kinetochore external link
level 6: nucleocytoplasmic transport external link
level 9: negative regulation of protein import into nucleus during spindle assembly checkpoint external link
level 9: activation of mitotic cell cycle spindle assembly checkpoint external link
GO Terms:
Molecular Function
level 3: protein-containing complex binding external link
GO Terms:
Cellular Component
level 4: nuclear envelope external link
level 4: kinetochore external link
level 5: nucleus external link
level 6: mitotic spindle external link
External source Open in SGD external link
w3c xhtml validator w3c css validator