S.cerevisiae - Yeastract

Gene Ontology Information

Protein Name	Vps45p
Description	Protein of the Sec1p/Munc-18 family; essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment; mutation in human VPS45 is associated with congenital neutropenia and primary myelofibrosis of infancy
GO Terms: Biological Process	level 4: cytoplasm to vacuole transport by the Cvt pathway level 5: protein transport level 5: vesicle-mediated transport level 5: intracellular protein transport level 6: protein targeting to vacuole level 6: Golgi to endosome transport level 6: Golgi to vacuole transport level 6: vacuole organization level 7: positive regulation of SNARE complex assembly level 7: Golgi vesicle fusion to target membrane level 7: vacuole inheritance level 11: vacuolar acidification
GO Terms: Molecular Function	level 4: SNARE binding level 4: unfolded protein binding
GO Terms: Cellular Component	level 3: cytoplasm level 3: membrane level 3: extrinsic component of membrane level 3: cytosol level 4: vacuole level 4: SNARE complex level 5: Golgi membrane level 5: vacuolar membrane
External source	Open in SGD