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Gene Ontology Information

Protein Name Nab2p
Description Nuclear polyadenylated RNA-binding protein; required for nuclear mRNA export and poly(A) tail length control; stimulates RNA polymerase III transcription by enhancing TFIIIB binding to promoters; dimerizes upon RNA binding; protects mRNA against decay by nuclear exosome in a poly(A)-tail-dependent manner; involved in forming export-competent mRNPs in the nucleus; autoregulates mRNA levels; NLS binds Kap104p; protein abundance increases under DNA replication stress; related to human hnRNPs
GO Terms:
Biological Process
level 5: regulation of mRNA stability external link
level 7: poly(A)+ mRNA export from nucleus external link
level 7: negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay external link
level 8: mRNA polyadenylation external link
level 9: positive regulation of transcription by RNA polymerase III external link
level 11: negative regulation of mRNA polyadenylation external link
GO Terms:
Molecular Function
level 5: RNA binding external link
level 5: metal ion binding external link
level 6: 7S RNA binding external link
level 6: tRNA binding external link
level 6: ribonuclease P RNA binding external link
level 6: mRNA binding external link
level 7: zinc ion binding external link
level 7: 5S rRNA binding external link
level 8: poly(A) binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
level 5: nucleus external link
External source Open in SGD external link
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