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Gene Ontology Information

Protein Name Hul5p
Description Multiubiquitin chain assembly factor (E4); proteasome processivity factor that elongates polyUb chains on substrates, opposing Ubp6p, a branched polyubiquitin protease; required for retrograde transport of misfolded proteins during ERAD; required for ubiquitination of a subset of cytosolic misfolded proteins upon heat shock
GO Terms:
Biological Process		 level 5: free ubiquitin chain polymerization external link
level 7: ubiquitin-dependent ERAD pathway external link
level 8: ubiquitin-dependent protein catabolic process external link
level 8: protein ubiquitination external link
level 9: protein polyubiquitination external link
GO Terms:
Molecular Function		 level 3: transferase activity external link
level 5: ubiquitin-protein transferase activity external link
level 6: ubiquitin protein ligase activity external link
level 7: ubiquitin-ubiquitin ligase activity external link
GO Terms:
Cellular Component		 level 3: cytoplasm external link
level 3: cytosol external link
level 4: proteasome complex external link
level 5: nucleus external link
External source Open in SGD external link
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