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Gene Ontology Information

Protein Name Cup2p
Description Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations; required for regulation of copper genes in response to DNA-damaging reagents; CUP2 has a paralog, HAA1, that arose from the whole genome duplication
GO Terms:
Biological Process
level 6: response to copper ion external link
level 7: regulation of DNA-templated transcription external link
level 8: regulation of transcription by RNA polymerase II external link
level 9: cellular copper ion homeostasis external link
level 9: cellular iron ion homeostasis external link
level 9: positive regulation of transcription by RNA polymerase II external link
GO Terms:
Molecular Function
level 3: DNA-binding transcription factor activity external link
level 4: DNA-binding transcription factor activity, RNA polymerase II-specific external link
level 5: DNA binding external link
level 5: metal ion binding external link
level 7: copper ion binding external link
level 7: zinc ion binding external link
level 8: RNA polymerase II cis-regulatory region sequence-specific DNA binding external link
GO Terms:
Cellular Component
level 5: nucleus external link
External source Open in SGD external link
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