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Gene Ontology Information

Protein Name Mpt5p
Description mRNA-binding protein of the PUF family; binds to specific mRNAs, often in the 3' UTR; has broad specificity and binds to more than 1000 mRNAs (16% of the transcriptome); recruits the CCR4-NOT deadenylase complex to mRNAs along with Dhh1p and Dcp1p to promote deadenylation, decapping, and decay; also interacts with the Caf20p translational initiation repressor, affecting its mRNA target specificity
GO Terms:
Biological Process
level 5: intracellular mRNA localization external link
level 7: positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay external link
level 7: positive regulation of mRNA binding external link
level 7: regulation of G1 to G0 transition external link
level 7: post-transcriptional regulation of gene expression external link
level 8: negative regulation of translation external link
level 9: negative regulation of translational initiation external link
GO Terms:
Molecular Function
level 3: protein-macromolecule adaptor activity external link
level 5: RNA binding external link
level 6: mRNA binding external link
GO Terms:
Cellular Component
level 3: cytoplasm external link
External source Open in SGD external link
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